KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXN
All Species:
23.94
Human Site:
S243
Identified Species:
43.89
UniProt:
P49023
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49023
NP_001074324.1
591
64533
S243
T
V
N
Q
G
E
M
S
S
P
Q
R
V
T
S
Chimpanzee
Pan troglodytes
XP_001159942
589
64154
S241
T
V
N
Q
G
E
M
S
S
P
Q
R
V
T
S
Rhesus Macaque
Macaca mulatta
XP_001085795
563
61555
S249
T
V
N
Q
G
E
M
S
S
P
Q
R
V
T
S
Dog
Lupus familis
XP_543425
664
72715
S254
T
V
N
Q
G
E
M
S
S
P
Q
R
V
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI36
591
64458
S243
T
V
N
Q
G
E
M
S
S
P
Q
R
V
T
S
Rat
Rattus norvegicus
Q66H76
586
64001
N234
M
K
E
K
P
K
R
N
G
G
R
G
L
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49024
559
61224
S244
T
V
S
Q
G
E
V
S
S
P
Q
R
V
N
A
Frog
Xenopus laevis
Q2TCH4
506
55983
K204
A
P
T
P
K
S
F
K
V
V
S
A
P
G
H
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
A117
S
T
A
I
N
K
M
A
R
P
F
S
A
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523601
581
64668
Y231
I
V
Q
Q
K
D
S
Y
T
P
N
H
A
V
P
Honey Bee
Apis mellifera
XP_624308
559
62451
H228
K
L
I
S
A
N
R
H
L
S
R
I
N
S
S
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
V111
V
Q
S
L
L
S
Q
V
E
E
P
P
I
R
A
Sea Urchin
Strong. purpuratus
XP_780574
695
76058
P326
M
T
N
S
T
H
A
P
P
Q
A
S
Q
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
83.1
N.A.
93.7
74.9
N.A.
N.A.
84.7
41.2
21.6
N.A.
43.1
43.3
33.8
43.4
Protein Similarity:
100
99.1
92.8
85.2
N.A.
95.7
78.3
N.A.
N.A.
88.4
54.3
36.5
N.A.
54.8
57
47
56.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
73.3
0
13.3
N.A.
20
6.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
N.A.
93.3
0
40
N.A.
33.3
26.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
8
8
0
0
8
8
16
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
8
0
0
47
0
0
8
8
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
47
0
0
0
8
8
0
8
0
8
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
8
% H
% Ile:
8
0
8
8
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
8
8
0
8
16
16
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
8
0
0
0
8
0
0
0
8
0
0
% L
% Met:
16
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
47
0
8
8
0
8
0
0
8
0
8
8
0
% N
% Pro:
0
8
0
8
8
0
0
8
8
62
8
8
8
8
16
% P
% Gln:
0
8
8
54
0
0
8
0
0
8
47
0
8
0
8
% Q
% Arg:
0
0
0
0
0
0
16
0
8
0
16
47
0
8
0
% R
% Ser:
8
0
16
16
0
16
8
47
47
8
8
16
0
16
47
% S
% Thr:
47
16
8
0
8
0
0
0
8
0
0
0
0
39
0
% T
% Val:
8
54
0
0
0
0
8
8
8
8
0
0
47
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _